Factors influencing the formation of Robison ester

Abstract

Reducing compounds increase Robison ester formation in muscle extract. Oxidising compounds have the reverse effect. These compounds attack the enzyme-forming Robison ester from glucose-l-phosphate (Cori ester). SS glutathione was used as oxidising compound. Alloxan acts like SS glutathione; it also inhibits Cori ester formation; its action is similar to caffeine. The inhibition by SS glutathione is completely reversed, by SH glutathione, the alloxan effect is partially reversed, the caffeine effect remains uninfluenced. Co acts like SH glutathione, Zn like SS glutathione.