Recurrent Meningococcemia Associated with IgG2-Subclass Deficiency

Abstract

To the Editor: We recently encountered a child who had repeated episodes of meningococcal infection at 6 and 14 months of age. He was first seen in January 1982 because of fever and rash. Examination revealed an infant with an apparent severe infection, a rectal temperature of 38.33°C (101°F), and a diffuse macular morbilliform exanthem with a few scattered petechiae. The patient was admitted for treatment and evaluation of suspected meningitis, which was subsequently determined by culture to be Neisseria meningitidis, untypable. He responded promptly to parenteral antibiotic therapy and had an uneventful recovery. The family was treated with . . .