The aim of this study was to determine feasibility, safety and yield of early stress tests after successful coronary angioplasty. In 351 consecutive patients with an early stress test performed within 3 days after successful coronary angioplasty, no cardiac or puncture site complications occurred. Seventeen percent of the stress tests remained positive after successful coronary angioplasty. An angiographic explanation, based on the data collected at the time of the angioplasty procedure, was present in 82% of the cases. Positive early stress tests typically only prompted modifications of the drug regimen.