Identification of synaptic acetylcholine receptor sites in retina with peroxidase-labeled α-bungarotoxin
- 1 August 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (8), 3268-3272
- https://doi.org/10.1073/pnas.74.8.3268
Abstract
An .alpha.-bungarotoxin-horseradish peroxidase conjugate, which bound specifically to nicotinic acetylcholine receptors, was synthesized. This conjugate was bound by 5-7% of the synapses in the inner plexiform layer of the chicken retina. Bipolar ribbon synapses and amacrine synapases bound the conjugate.Keywords
This publication has 25 references indexed in Scilit:
- Immunochemical studies on acetylcholine receptor from Torpedo californicaImmunochemistry, 1977
- THE DISTRIBUTION OF CHOLINE ACETYLTRANSFERASE ACTIVITY IN VERTEBRATE RETINA1Journal of Neurochemistry, 1976
- The density of cholinergic receptors at the endplate postsynaptic membrane: Ultrastructural studies in two mammalian speciesThe Journal of Membrane Biology, 1975
- Immunoperoxidase staining of α-bungarotoxin binding sites in muscle endplates shows distribution of acetylcholine receptorsNature, 1975
- DIFFUSION ARTIFACTS IN 3,3'-DIAMINOBENZIDINE CYTOCHEMISTRYJournal of Histochemistry & Cytochemistry, 1972
- Irreversible binding of a krait neurotoxin to membrane proteins from eel electroplax and hog brainBiochemical and Biophysical Research Communications, 1972
- Peroxidase labelled antibody and Fab conjugates with enhanced intracellular penetrationImmunochemistry, 1971
- Amino acid sequence of α-bungarotoxin from the venom of bungarus multicinctusBiochemical and Biophysical Research Communications, 1971
- The inner plexiform layer of the vertebrate retina: A quantitative and comparative electron microscopic analysisJournal of Comparative Neurology, 1970
- PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSESThe Journal of Experimental Medicine, 1954