Cyclic AMP Concentration and Enzyme Activities of Cerebrospinal Fluid in Patients with Epilepsy or Central Nervous System Damage

Abstract

Cyclic adenosine-3’,5’-monophosphate (cAMP) concentration in cerebrospinal fluid (CSF) was measured by the protein binding method of Gilman from 62 neurological patients, 46 of them were epileptics and 16 with a central nervous system (CNS) damage. In epileptic patients the CSF concentration of cAMP was significantly elevated (p