Down's syndrome in Western Australia: Cytogenetics and incidence
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 48 (1), 67-72
- https://doi.org/10.1007/bf00273276
Abstract
235 cases of Down's syndrome were ascertained in a 10-year study of Down's syndrome in Western Australia. Although cytogenetic studies performed on 222 subjects confirmed that 95% of cases were trisomic due to nondisjunction, 4% were trisomic due to translocation, and 1% were mosaic, the ratio of inherited/sporadic translocations differed from that usually reported. Comparison of the results with those of an earlier Australian survey of Down's syndrome demonstrated a real fall in the incidence of Down's syndrome in Australia but no significant change in maternal age-specific incidences.This publication has 22 references indexed in Scilit:
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