Abstract
During the summer of 330b.c.Alexander the Great pursued the Persian king Darius III through Northern Media, past the Caspian Gates, and eastward into the Achaemenid satrapy of Parthava (Parthia). Upon reaching Darius, Alexander found the king murdered by the usurper Bessus. The Macedonian thereafter advanced east for three more days until he arrived at the wealthy city which was later to be called Hecatompylos. It is the problems of Hecatompylos and the several related questions of its home district, called Comisene by the Greeks, which this paper will consider.

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