Fractionation and Biological Actions of Pituitary Gonadotropins from a Marsupial, the Wallaby (Macropus eugenhl)1
- 1 October 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 19 (3), 680-687
- https://doi.org/10.1095/biolreprod19.3.680
Abstract
Fractionation of pituitaries from a macropod marsupial, the wallaby (Macropus eugenii), yielded two distinct types of gonadotropins whose biological profiles, chromatographic behavior and amino acid composition resembled the follicle stimulating hormone (FSH) and luteinizing hormone (LH) of eutherian species. Also, the wallaby LH showed complete immunological cross reactivity in a homologous radioimmunoassay for ovine LH, while only wallaby FSH crossreacted in a heterologous radioimmunoassay based on anti-ovine FSH and 125I-labeled human or rat FSH. The purified wallaby FSH was relatively potent in Steelman-Pohley bioassay (ca. 10-20 units NIH-FSH-S1/mg), while the wallaby LH showed little activity (<1.2 units/mg.)This publication has 9 references indexed in Scilit:
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