The Role of “Folic Acid” and Biotin in the Nutrition of the Rat
- 1 June 1943
- journal article
- research article
- Published by Elsevier BV in Journal of Nutrition
- Vol. 25 (6), 555-570
- https://doi.org/10.1093/jn/25.6.555
Abstract
The inhibition of growth and increase in prothrombin time brought about by the inclusion of succinylsulfathiazole in highly purified rations adequate in the well-recognized members of the vitamin B complex could be largely overcome by supplements of a “folic acid” concentrate and crystalline biotin. The relationship of “folic acid” and biotin to bacterial activity in the intestine is discussed.Keywords
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