The Role of “Folic Acid” and Biotin in the Nutrition of the Rat
- 1 June 1943
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 25 (6), 555-570
- https://doi.org/10.1093/jn/25.6.555
Abstract
The inhibition of growth and increase in prothrombin time brought about by the inclusion of succinylsulfathiazole in highly purified rations adequate in the well-recognized members of the vitamin B complex could be largely overcome by supplements of a “folic acid” concentrate and crystalline biotin. The relationship of “folic acid” and biotin to bacterial activity in the intestine is discussed.Keywords
This publication has 18 references indexed in Scilit:
- Biotin Deficiency and Other Changes in Rats Given Sulfanilylguanidine or Succinyl Sulfathiazole in Purified DietsScience, 1942
- THE TREATMENT OF TYPHOID AND DYSENTERY CARRIERS WITH SUCCINYLSULFATHIAZOLEJAMA, 1942
- Folic Acid in the Growth of Cl. tetaniExperimental Biology and Medicine, 1942
- The Occurrence of Hyaline Sclerosis and Calcification of Blood Vessels in Rats on SulfaguanidinePublic Health Reports®, 1942
- Succinyl Sulfathiazole, a New Bacteriostatic Agent Locally Active in the Gastrointestinal TractExperimental Biology and Medicine, 1941
- THE CONCENTRATION OF “FOLIC ACID”Journal of the American Chemical Society, 1941
- Use of Sulfaguanidine in Nutrition Experiments.Experimental Biology and Medicine, 1941
- The Number of Vitamins Required by the Rat.Experimental Biology and Medicine, 1941
- Reproduction in Rats on Synthetic B-Complex Supplement.Experimental Biology and Medicine, 1940
- STUDIES ON THE VITAMIN K REQUIREMENTS OF THE RATAmerican Journal of Physiology-Legacy Content, 1939