The Effect of Thyroprotein Feeding on the Blood Level of Inorganic Iodine, Protein-Bound Iodine and Cholesterol in Dairy Cows
Open Access
- 1 October 1953
- journal article
- research article
- Published by American Dairy Science Association in Journal of Dairy Science
- Vol. 36 (10), 1049-1057
- https://doi.org/10.3168/jds.s0022-0302(53)91596-3
Abstract
Changes in blood serum protein-bound I2 (PBI) found under normal conditions to reflect the amt. of thyroid hormone in the blood, and plasma cholesterol, shown to have an inverse relationship to thyroid activity, were measured during and after feeding of different dosages of thyroprotein (Protamone) to dairy cows. Inorganic I2 and blood sugar detns also were made. During thyroprotein feeding both inorganic I2 and PBI values increased tremendously above the normal range. After thyroprotein feeding was ended, inorganic I2 decreased rapidly to normal whereas PBI persisted for several mos. at a level higher than prefeeding values. Plasma cholesterol decreased for a time during thyroprotein feeding and then gradually returned to normal. After thyroprotein feeding was terminated, cholesterol rose above the normal level and then gradually returned to normal. Although plasma cholesterol appeared to reflect more accurately the thyroid status of the cows than did PBI, particularly after thyroprotein feeding was ended, neither of these blood constituents could be accurately correlated with dosage of thyroprotein. The possible reasons for these changes are discussed. No changes in blood sugar due to thyroprotein feeding were observed. The injn. of thyrotropic hormone into a steer resulted in an increase in PBI without any increase in inorganic I2. This is further indication that PBI does reflect thyroid status when thyroid activity is increased without the interference of noncalorigenic PBI.This publication has 13 references indexed in Scilit:
- The Relationship of Serum Protein Bound Iodine Levels to Rates of Gain in Beef CattleJournal of Animal Science, 1953
- Protein-Bound Iodine Levels in Dairy Cattle PlasmaJournal of Dairy Science, 1953
- Bovine Protein-Bound Serum Iodine and its Relation to Age and BreedJournal of Dairy Science, 1952
- Seruni Precipitable and Butanol Extractable Iodine of Bovine SeraExperimental Biology and Medicine, 1952
- Endocrine Review: THE CLINICAL SIGNIFICANCE OF THE BLOOD IODINE: A REVIEW*Journal of Clinical Endocrinology & Metabolism, 1950
- IODINE IN NUTRITIONJAMA, 1949
- Distribution of Cholesterol, Cholesterol Esters and Phospholipid Phosphorus in Blood in Thyroid DiseaseExperimental Biology and Medicine, 1946
- The clinical significance of cholesterolDigestive Diseases and Sciences, 1945
- THE THYROID AND ITS DISEASESThe American Journal of the Medical Sciences, 1938
- STUDIES ON BLOOD LIPOIDSArchives of Internal Medicine, 1922