Neurotensin-like immunoreactivity in some preparations of secretin and cholecystokinin

Abstract

Commercially available cholecystokinin (CCK) from the Boots Company, Nottingham and to a lesser degree CCK from the Gastrointestinal Hormone Research Unit of Karolinska Institute Stockholm and from Kabi Diagnostica, Studsvik, and also secretin from the Boots Company have been found to contain neurotensin-like immunoreactive contamination. As neurotensin is able to stimulate pancreatic secretion, this admixture may be of relevance when pancreatic function is tested.