β-GLUCURONIDASE STUDIES IN INBRED MICE: ANDROGENIC HORMONES AND KIDNEY AND URINARYβ-GLUCURONIDASE ACTIVITY12

Abstract

Testosterone propionate increased by substantial amts. the excretion of beta-glucuronidase in the urine of mice. This phenomenon was accompanied by the simultaneous elevation of beta-glucuronidase activity in the kidney tubules. Under the conditions of the expts., significant augmentation in both renal and urinary beta-glucuronidase of androgen-treated DBA mice was observed by the 3d exptl. day.