Using GeneWise in the Drosophila Annotation Experiment
Open Access
- 1 April 2000
- journal article
- research article
- Published by Cold Spring Harbor Laboratory in Genome Research
- Vol. 10 (4), 547-548
- https://doi.org/10.1101/gr.10.4.547
Abstract
The GeneWise method for combining gene prediction and homology searches was applied to the 2.9-Mb region from Drosophila melanogaster. The results from the Genome Annotation Assessment Project (GASP) showed that GeneWise provided reasonably accurate gene predictions. Further investigation indicates that many of the incorrect gene predictions from GeneWise were due to transposons with valid protein-coding genes and the remaining cases are pseudogenes or possible annotation oversights.Keywords
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