Quantitative determination of haemoglobin A2using paper electrophoresis

Abstract
A quantitative paper electrophoresis method for the separation of haemoglobins A and A2 is described. The possible sources of error and the accuracy of the method have been investigated. The normal range for haemoglobin A2 by this method is 1·3% to 4·3% of the total haemoglobin concentration. Good clinical correlation has so far been obtained.