ELECTROPHORETIC VARIATION FOR X-CHROMOSOME-LINKED PHOSPHOGLYCERATE KINASE (PGK-1) IN THE MOUSE
Open Access
- 1 October 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 87 (2), 319-325
- https://doi.org/10.1093/genetics/87.2.319
Abstract
Electrophoretic variation for X-chromosome-linked phosphoglycerate kinase (PGK-1) has been found as a polymorphism in feral mice in Denmark. Males from feral sampling or from a variety of genetic crosses have only a single-banded phenotype of the variant PGK-1A type or of the PGK-1B type commonly found among inbred mice. By contrast, three phenotypes were observed among females; two homozygous single-banded types and a heterozygous double-banded type. The X-chromosome linkage of the Pgk-1 locus was determined from the mode of inheritance in F1 and backcross generations and confirmed by the linkage of Pgk-1 and the X-linked markers Hq, Ta and Mo. Pgk-1 showed 29/122 recombinations with Hq, 5/185 with Ta and 0/108 recombinants with Mo. Based on these recombination data, a gene order of Hq—Ta—Pgk-1—Mo is suggested.This publication has 10 references indexed in Scilit:
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