Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors
- 1 June 1999
- journal article
- Published by Elsevier in Chemistry & Biology
- Vol. 6 (6), 361-375
- https://doi.org/10.1016/s1074-5521(99)80048-9
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Solution-phase synthesis of 2,6,9-trisubstituted purinesTetrahedron Letters, 1998
- Synthesis and activity of 2,6,9-trisubstituted purinesBioorganic & Medicinal Chemistry Letters, 1997
- The Effect of the Cyclin-Dependent Kinase Inhibitor Olomoucine on Cell Cycle KineticsExperimental Cell Research, 1997
- Facile Preparation of 2,6-Disubstituted Purines Using Solid-Phase ChemistryThe Journal of Organic Chemistry, 1997
- Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5European Journal of Biochemistry, 1997
- A Structure-Based Library Approach to Kinase InhibitorsJournal of the American Chemical Society, 1996
- Cyclin‐dependent protein kinases: Key regulators of the eukaryotic cell cycleBioEssays, 1995
- Inhibition of Cyclin‐Dependent Kinases by Purine AnaloguesEuropean Journal of Biochemistry, 1994
- The Alkylation of 2-Amino-6-chloropurine with Alcohols by Mitsunobu Reaction for a Synthesis of Carbocyclic Guanosine AnalogsHETEROCYCLES, 1993
- Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell killJournal of Immunological Methods, 1989