Levels of 5,5-Diphenylhydantoin and its Major Metabolite in Human Serum, Saliva, and Hyperplastic Gingiva
- 1 November 1974
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 53 (6), 1323-1329
- https://doi.org/10.1177/00220345740530060401
Abstract
Levels of 5,5-diphenylhydantoin (DPH) and its para-hydroxy metabolite (HPPH) were measured in serum, saliva, and in segments of hyperplastic gingiva from patients receiving chronic drug therapy. The severity of gingival hyperplasia tends to be associated with higher DPH levels in gingiva and with lower tissue levels of HPPH.Keywords
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