Clinical and subclinical Barmah Forest virus infection in Queensland

Abstract

Barmah Forest virus is a mosquito-borne agent (alphavirus) reported to cause both clinical and subclinical infections in New South Wales. This report describes 29 cases of clinical Barmah Forest virus infection diagnosed between July 1988 and March 1989 (21 from Queensland, six from New South Wales and two from Victoria) and provides evidence of extensive subclinical infection with this virus (0.23% of the population per annum) throughout Queensland. It also includes a description of the first isolation of Barmah Forest virus from a patient. Data obtained in the course of the study suggest that Barmah Forest virus infections may not be diagnosed correctly in many instances because of the similarity of the symptoms of this disease to those of epidemic polyarthritis and the small number of laboratories providing the necessary serological services.