Opposite Effects of Extracellular Sodium Removal on the Uptake of Tryptophan into Rat Cortical Slices and Synaptosomes
- 1 July 1984
- journal article
- Published by Wiley in Journal of Neurochemistry
- Vol. 43 (1), 274-275
- https://doi.org/10.1111/j.1471-4159.1984.tb06708.x
Abstract
The removal of extracellular sodium decreased L-tryptophan (L-TRP) uptake into brain slices but increased uptake into synaptosomes. The uptake of 5-hydroxytryptamine (5-HT) was inhibited in both preparations under these conditions. It is suggested that the different effects on L-TRP uptake may be due to differences in cellular composition between the two preparations rather than to any differences in sample handling.Keywords
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