Ketamine was used as the sole anesthetic agent for vaginal delivery in 80 women. Complete analgesia occurred in 78, partial analgesia in one, and one had no effects. Administered intravenously immediately before delivery in doses of 12.5 to 25 mg. (0.2 to 0.4 mg./kg.) with a dosage limit of 100 mg., ketamine administration resulted in no significant maternal or newborn complications.