Abstract
Human adults (22) with low-grade (Grade I or II) astrocytomas of the cerebrum underwent initial computed tomography (CT) and craniotomy followed by irradiation of 5000-6000 rad (50-60 Gy [gray]). The 4 yr actuarial of life table survival rate was 58% for the 8 patients whose initial CT scans showed contrast enhancement and 65% for the 14 patients whose tumors did not enhance (P = 0.8). Prognostic factors were comparable for the 2 groups. Contrast enhancement has no prognostic significance for low-grade astrocytomas of the adult cerebrum.