Growth of chromosome ends in multiplying trypanosomes
- 1 June 1983
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 303 (5918), 592-597
- https://doi.org/10.1038/303592a0
Abstract
Some of the genes for the variant surface glycoproteins of trypanosomes are located close to a discontinuity in the DNA, presumably a chromosome end. We show here that DNA fragments containing these telomeres increase in length in multiplying trypanosomes at a rate of about 10 base pairs per division. We argue that chromosome growth may not be restricted to trypanosomes and could explain the heterogeneity of telomeric DNA fragments observed in some other organisms.This publication has 45 references indexed in Scilit:
- Inverted terminal repeats are added to genes during macronuclear development in Oxytricha nova.Proceedings of the National Academy of Sciences, 1982
- Cloning yeast telomeres on linear plasmid vectorsCell, 1982
- Incompletely base-paired flip-flop terminal loops link the two DNA strands of the vaccinia virus genome into one uninterrupted polynucleotide chainCell, 1982
- Repeated hexanucleotide C-C-C-C-A-A is present near free ends of macronuclear DNA of Tetrahymena.Proceedings of the National Academy of Sciences, 1981
- An irregular satellite sequence is found at the termini of the linear extrachromosomal rDNA in Dictyostelium discoideumCell, 1981
- Yeast transformation: a model system for the study of recombination.Proceedings of the National Academy of Sciences, 1981
- A family of inverted repeat sequences and specific single-strand gaps at the termini of the Physarum rDNA palindromeCell, 1980
- A molecular description of telomeric heterochromatin in secale speciesCell, 1980
- Isolation and characterization of a highly repetitious inverted terminal repeat sequence from Oxytricha macronuclear DNA.Proceedings of the National Academy of Sciences, 1978
- A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in TetrahymenaJournal of Molecular Biology, 1978