Association Between Sustained Virological Response and All-Cause Mortality Among Patients With Chronic Hepatitis C and Advanced Hepatic Fibrosis

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Abstract
Chronic hepatitis C virus (HCV) infection is a major cause of cirrhosis, hepatocellular carcinoma (HCC), and end-stage liver disease. The incidence of HCV-related cirrhosis and its complications is expected to increase in upcoming years.1,2 Davis et al2 estimated that currently 25% of the approximately 3.5 million US patients with chronic HCV infection have cirrhosis and that the proportion of patients with cirrhosis is likely to increase up to 45% by 2030.