Epidermal Papillomas with Virus-like Particles in Flathead Sole, Hippoglossoides elassodon

Abstract
Epidermal papillomas frequently occur on the external surfaces of flathead sole, Hippoglossoides elassodon, in the waters of San Juan Islands, Washington. Virus-like particles and associated granular bodies, also of possible viral nature, are commnonly found in the neoplastic epithelial cells of these tumors. Similar structures are not observed in normal epidermis.