Leiner's Disease Associated with Diminished Third Component of Complement
- 1 August 1987
- journal article
- case report
- Published by Wiley in Pediatric Dermatology
- Vol. 4 (2), 105-107
- https://doi.org/10.1111/j.1525-1470.1987.tb00762.x
Abstract
A 6-week-old female infant experienced recurrent diarrhea, wasting, and generalized seborrheic dermatitis. She manifested defective yeast opsonization and concomitant very low level of the third component of complement (C3). This is the first report of Leiner's disease associated with diminished C3. It corroborates evidence to suggest that yeast opsonic activity of normal human serum is dependent on C3 levels.Keywords
This publication has 7 references indexed in Scilit:
- Defective yeast opsonisation and functional deficiency of complement in sickle cell disease.Archives of Disease in Childhood, 1982
- Yeast opsonization defect and immunoglobulin deficiency in severe infantile dermatitis (Leiner's disease).Archives of Disease in Childhood, 1977
- Hereditary deficiency of the fifth component of complement in man. II. Biological properties of C5-deficient human serum.Journal of Clinical Investigation, 1976
- Defective opsonization. A common immunity deficiency.Archives of Disease in Childhood, 1976
- Human C3 and C5: Subunit Structure and Modifications by Trypsin and C4̄2̄-C4̄2̄3̄The Journal of Immunology, 1975
- A Familial Deficiency of the Phagocytosis-Enhancing Activity of Serum Related to a Dysfunction of the Fifth Component of Complement (C5)New England Journal of Medicine, 1970
- Über Erythrodermia desquamativa, eine eigenartige universelle Dermatose der BrustkinderArchives of Dermatological Research, 1908