Several cases of chloric acne were observed in children after accidental Seveso TCDD [tetrachloro-2,3,7,8-dibenzo-p-dioxin] intoxication. The lesions consist in an inflammatory hyperkeratotic erythema of exposed areas, with numerous horny cysts, sometimes associated with granuloma annulare aspects of the hands. All lesions have the same histological pattern and atrophoderma vermiculata is often their ultimate evolution. These cases are similar to the epidemic follicular keratosis observed in 1946 around Bale in Switzerland; thus the clinical and genetic evolution of these patients may be foreseen.