The dermatology service of Cleveland City Hospital admitted 1881 adult male patients to its wards from July 1, 1924 to Jan. 1, 1929, an interval of four and a half years; 1098 of these cases presented penile lesions; 537, or 49 per cent, of these genital lesions were chancroidal infections. The average age of the patients with chancroidal lesions was 27. Three fifths of the cases occurred in negroes. The service has had recourse to all the time-honored local and constitutional therapeusis, such as soaks, irrigations, iodoform, caustics, electrocautery, hygiene and rest in bed. The lengthy tedious treatment offered, at best, 50 per cent of cases of complicating suppurative inguinal adenitis which the patient either brought in with him or developed under therapy. More than 26 per cent of the total number of suppurating glands developed during this type of therapy. Gradually sufficient evidence was accumulated to formulate certain axioms: