Field Study of the Prophylactic Value of Pertussis Vaccine

Abstract

In a controlled field study of the prophylactic value of a Phase I pertussis vaccine, conducted in Binghamton, New York, Jan. 1, 1939, to Nov. 1, 1940, the following results were obtained: The study involved 587 vaccinated children and 699 control children, aged 6 mos., through 4 yrs. During the period of observation the pertussis attack rate was more than twice as high in the control group as in the vaccinated group, and the cases of pertussis which did occur among the vaccinated group were distinctly less severe than those which occurred among the control children.