Cyclic 3',5'-adenosine monophosphate phosphodiesterase of Escherichia coli.

  • 1 November 1973
    • journal article
    • Vol. 116 (2), 857-66
Abstract
The cyclic 3',5'-adenosine monophosphate (c-AMP) phosphodiesterase from Escherichia coli has been partially purified. The enzyme has an apparent molecular weight of 30,000, a Michaelis constant of 0.5 mM c-AMP, and a pH optimum of 7. The partially purified enzyme requires for activity the presence of a reducing compound and of either iron or a protein which seemingly acts as iron carrier.

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