THE PRESENT report traces for another year the histories of patients with duodenal ulcer who had a subdiaphragmatic vagus resection with posterior gastroenterostomy between September, 1946, and April, 1949. During this period, other types of operation were being performed for duodenal ulcer, but after preliminary trial, vagus resection with gastroenterostomy became the dominating procedure. This series is consecutive for vagus resection with gastroenterostomy for duodenal ulcer. The report is based upon a group of 146 patients, followed for a minimum of three years; 56 patients have been followed five years, 59 have been followed four years, and 31 have been followed three years. Eight patients could not be traced this year, with the result that the follow-up is 95% complete. MATERIAL During the period in question, about 13.5% of all patients with duodenal ulcer seen and treated at the Cleveland Clinic had some type of operation performed. The medical treatment