Angio-immunoblastic lymphadenopathy terminating as Hodgkin's disease
- 1 May 1977
- Vol. 39 (5), 2183-2189
- https://doi.org/10.1002/1097-0142(197705)39:5<2183::aid-cncr2820390535>3.0.co;2-7
Abstract
The clinical course of a 33‐year‐old man with generalized lymphadenopathy bearing all physical, laboratory and histologic characteristics of “angio‐immunoblastic lymphadenopathy with dysproteinemia” (AILD) is described. Therapy was without significant benefit and the patient died 22 months after initial diagnosis. At autopsy in addition to the characteristic cellular polymorphism of AILD, numerous Hodgkin's cells and Sternberg‐Reed cells were identified in the lymph nodes and spleen. Pleomorphic cellular infiltrates containing an increased number of immunoblasts and some giant cells were found also in the portal spaces of the liver. The evolution of Hodgkin's disease (H.D.) from AILD suggests that the latter may have represented a reaction to the agent which causes H.D.This publication has 13 references indexed in Scilit:
- Angio-immunoblastic lymphadenopathyThe American Journal of Medicine, 1975
- Immunoblastic LymphadenopathyNew England Journal of Medicine, 1975
- Lymphadenopathy simulating the malignant lymphomasHuman Pathology, 1974
- ANGIO-IMMUNOBLASTIC LYMPHADENOPATHY WITH DYSPROTEINÆMIAThe Lancet, 1974
- Relations between Immunity and MalignancyProceedings of the National Academy of Sciences, 1972
- Sjögren's Syndrome—Newer Aspects of Research, Diagnosis, and TherapyAnnals of Internal Medicine, 1971
- Genetically determined immune deficiency as the predisposing cause of “autoimmunity” and lymphoid neoplasiaAmerican Journal Of Medicine, 1971
- Postvaccinial lymphadenitis.Hyperplasia of lymphoid tissue that simulates malignant lymphomasCancer, 1968
- Lymphogranulomatosen mit konstant hohem EpitheloidzellgehaltVirchows Archiv, 1968
- AUTO-IMMUNITY IN MAN AND HOMOLOGOUS DISEASE IN MICE IN RELATION TO THE MALIGNANT LYMPHOMASThe Lancet, 1959