Spasmolytic Activity of Angelicin: A Coumarin fromHeracleum thomsoni1

Abstract

Angelicin, a coumarin isolated from the aerial parts of Heracleum thomsoni, showed nonspecific spasmolytic activity in a variety of in vivo and in vitro test models and was also orally active. In most of the test systems it was found to be equipotent to papaverine.