Insertion Sequence Duplication in Transpositional Recombination
- 18 November 1983
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 222 (4625), 755-765
- https://doi.org/10.1126/science.6314502
Abstract
Insertion sequences (IS) are discrete segments of DNA that can transpose from one genomic site to another and promote genetic rearrangements. A question that is central to understanding the mechanism of transpositional recombination is whether genetic rearrangements are accompanied by duplication of the IS that promotes them. Analysis of adjacent deletions mediated by IS903 provides the strongest evidence to date than any IS-mediated transpositional recombination can occur by an efficient replicative mechanism.Keywords
This publication has 20 references indexed in Scilit:
- Transposition of Tn3 and related transposonsCell, 1983
- A novel type of transposon generated by insertion element Is102 present in a psc101 derivativeCell, 1982
- Structure and stability of Tn9-mediated cointegratesJournal of Molecular Biology, 1982
- TRANSPOSABLE ELEMENTS IN PROKARYOTESAnnual Review of Genetics, 1981
- recA-independent general genetic recombination of plasmidsNature, 1981
- Nucleotide sequence of the kanamycin resistance transposon Tn903Journal of Molecular Biology, 1981
- Site-specific deletions in the recombinant plasmid pSC101 containing the redB-ori region of phage λGene, 1981
- recA-dependent genetic switch generated by transposon Tn10Journal of Molecular Biology, 1980
- Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit β-globinCell, 1980
- Nucleotide sequence at the insertion sites of a kanamycin transposonNature, 1978