In Vivo Effects of Diagnostic X-Irradiation on Human Chromosomes
- 18 June 1964
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 270 (25), 1341-1344
- https://doi.org/10.1056/nejm196406182702504
Abstract
CHROMOSOMAL aberrations have been shown to persist for eighteen years in the peripheral leukocytes of patients exposed to therapeutic doses of x-irradiation for ankylosing spondylitis.1 Accidental exposure to mixed gamma and neutron radiation at doses of 23 to 365 rads was found by Bender and Gooch2 to produce chromosome effects lasting up to three and a half years after irradiation. Isolated case reports have described abnormally structured chromosomes in persons undergoing diagnostic x-ray examinations, in 1 case at a dose of 0.8 rad.3 , 4 The present study was designed to evaluate the possible chromosomal effects of different diagnostic x-ray procedures at . . .Keywords
This publication has 9 references indexed in Scilit:
- Transformation of Lymphocytes in Cultures of Human Peripheral BloodBlood, 1963
- A STUDY OF THE CHROMOSOME DAMAGE PERSISTING AFTER X-RAY THERAPY FOR ANKYLOSING SPONDYLITISThe Lancet, 1962
- The Kinetics of Cell Proliferation in Cultures of Human Peripheral BloodBlood, 1962
- CHROMOSOMAL ABERRATION AFTER DIAGNOSTIC X-IRRADIATIONThe Lancet, 1961
- Chromosome preparations of leukocytes cultured from human peripheral bloodExperimental Cell Research, 1960