Leka, a New Platelet Antigen Absent in Glanzmann's Thrombasthenia
- 1 January 1984
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 46 (1), 47-54
- https://doi.org/10.1111/j.1423-0410.1984.tb00047.x
Abstract
The serum of a patient who developed a posttransfusion purpura contained antibodies directed against a previously undescribed platelet antigen Leka. The antiplatelet activity was present in the IgG fraction and was detected by immunofluorescence, 51Cr lysis and 14C-serotonin release. The frequency of the Leka phenotype in the French population is 98.18%. Leka does not appear to be sex-linked and seems to be closely related to the Baka antigen. The Lek antigen is not expressed on thrombasthenic platelets but is found on platelets from patients with the Bernard-Soulier syndrome which suggests that this antigen is carried by platelet glycoproteins IIb and/or IIIa.This publication has 15 references indexed in Scilit:
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