Starch and talc emboli in drug addicts' lungs
Open Access
- 1 October 1972
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 25 (10), 876-881
- https://doi.org/10.1136/jcp.25.10.876
Abstract
The lungs of eight drug addicts dying as a consequence of their habit have been examined. All showed the presence of small amounts of talc emboli and five the presence of starch emboli. Talc was invariably associated with a marked foreign body reaction which was insignificant in association with starch. Animal experiments showed very rapid (90% in 24 hours) removal of maize starch emboli; such rapid removal in man would explain the lack of a foreign body response. Quantitation of the amount of starch present in lungs from two of the cases gave values of 1·5 and 5·2 g. The higher amount could have been a contributory factor in the sudden death of the addict. The amounts of talc seen were not sufficient to be of clinical significance.Keywords
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