Testosterone Response to Exercise during Blockade and Stimulation of Adrenergic Receptors in Man

Abstract

The effects of pharmacological stimulation or blockade of adrenergic receptors on plasma testosterone levels were studied in healthy men subjected to bicycle ergometer exercise. Plasma testosterone increase after exercise was of shorter duration when the alpha-blocker phentolamine was applied, whereas treatment with the alpha-agonist clonidine was without any effect. Blockade of beta-receptors by propranolol inhibited the testosterone response to exercise.