PREVENTION OF RENAL-FAILURE IN RATS RECEIVING CIS-DIAMMINEDICHLOROPLATINUM(II) BY ADMINISTRATION OF FUROSEMIDE

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 37 (4), 1238-1240
Abstract
The clinicopathological signs of renal failure induced in rats by weekly i.v. administration of the antitumor agent cis-diamminedichloroplatinum(II) were prevented by pretreatment with furosemide. Weight loss, anemia and generalized toxic effects of the drug were not effected by furosemide.