On‐chip tryptic digest with direct coupling to ESI‐MS using magnetic particles
- 1 December 2008
- journal article
- microfluidics and-miniaturization
- Published by Wiley in Electrophoresis
- Vol. 29 (24), 4944-4947
- https://doi.org/10.1002/elps.200800431
Abstract
As a step toward a fully automated front‐end microfluidic chip for MS proteomics, we propose a system capable of performing online tryptic digest and ESI‐MS, using a replaceable on‐chip digestion microcolumn based on self‐assembled magnetic particles.Keywords
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