A Modified Procedure for Determining Inulin Space.

Abstract

1. Inulin recovery was found to be incomplete in five hours after the termination of a two—hour inulin infusion. Since the unrecovered inulin amounted to an average of 15% of the inulin present in the dog at the time of equilibration, an equivalent error was introduced into the calculation of the inulin space by the method of Gaudino and Levitt. 2. By administering a solution made from pure, accurately weighed, dry inulin, and determining the inulin content of the urine excreted during the infusion, the amount of inulin remaining in the dog can be computed with an average error of only 3.8%. In addition, the time needed for urine collection is greatly reduced.