Autoencapsulation Through Intermolecular Forces: A Synthetic Self-Assembling Spherical Complex
- 1 December 1995
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 270 (5241), 1485-1488
- https://doi.org/10.1126/science.270.5241.1485
Abstract
The synthesis and characterization of a system for the study of molecular recognition phenomena are described. The system involves a tetraurea molecule that is capable of assembly into various associated states through hydrogen bonding. In organic solvents, the dynamic transition between a low-ordered (aggregate) state and a highly ordered dimeric assembly can be induced by the introduction of smaller molecules of appropriate size and shape. These smaller molecules, such as benzene, adamantanes, and ferrocenes, act as guests that occupy the pseudospherical capsule formed by the dimeric host. Among various guests, those that best fill the cavity and offer chemical complementarity to the host are preferentially encapsulated.Keywords
This publication has 17 references indexed in Scilit:
- Guest-Induced Organization of a Three-Dimensional Palladium(II) Cagelike Complex. A Prototype for "Induced-Fit" Molecular RecognitionJournal of the American Chemical Society, 1995
- The Structural and Thermodynamic Basis for the Formation of Self‐Assembled Peptide NanotubesAngewandte Chemie International Edition in English, 1995
- Self-Assembly through Hydrogen Bonding: Peripheral Crowding - A New Strategy for the Preparation of Stable Supramolecular Aggregates Based on Parallel, Connected CA3.cntdot.M3 RosettesJournal of the American Chemical Society, 1994
- Encapsulation of Methane and Other Small Molecules in a Self-Assembling SuperstructureScience, 1994
- Self-assembling organic nanotubes based on a cyclic peptide architectureNature, 1993
- Host-guest complexation. 65. Hemicarcerands that encapsulate hydrocarbons with molecular weights greater than two hundredJournal of the American Chemical Society, 1993
- Multicomponent Self‐Assembly: Spontaneous Formation of a Cylindrical Complex from Five Ligands and Six Metal IonsAngewandte Chemie International Edition in English, 1993
- Self-assembly of a hydrogen-bonded 2 + 3 supramolecular complexJournal of the American Chemical Society, 1991
- Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanicsJournal of Computational Chemistry, 1990
- Synthesis and Oxidation of 2-Amino-2,3-dihydro-1H-benz[de]isoquinoline and 1,2,3,4-Tetrahydronaphtho[1,8-de][1,2]diazepine and Related Cyclic 1,2-DibenzylhydrazinesJournal of the American Chemical Society, 1963