Insect Sex-Pheromone Signals Mediated by Specific Combinations of Olfactory Receptors
Top Cited Papers
- 11 March 2005
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 307 (5715), 1638-1642
- https://doi.org/10.1126/science.1106267
Abstract
We describe two male-specific olfactory receptors (ORs) in the silk moth, Bombyx mori, that are mutually exclusively expressed in a pair of adjacent pheromone-sensitive neurons of male antennae: One is specifically tuned to bombykol, the sex pheromone, and the other to bombykal, its oxidized form. Both pheromone ORs are coexpressed with an OR from the highly conserved insect OR subfamily. This coexpression promotes the functional expression of pheromone receptors and confers ligand-stimulated nonselective cation channel activity. The same effects were also observed for general ORs. Both odorant and pheromone signaling pathways are mediated by means of a common mechanism in insects.Keywords
This publication has 22 references indexed in Scilit:
- Odorant receptor heterodimerization in the olfactory system of Drosophila melanogasterNature Neuroscience, 2004
- The odor coding system of DrosophilaTrends in Genetics, 2004
- Or83b Encodes a Broadly Expressed Odorant Receptor Essential for Drosophila OlfactionNeuron, 2004
- The Molecular Basis of Odor Coding in the Drosophila AntennaCell, 2004
- Two-Photon Calcium Imaging Reveals an Odor-Evoked Map of Activity in the Fly BrainCell, 2003
- MECHANISMS OF OLFACTORY DISCRIMINATION: Converging Evidence for Common Principles Across PhylaAnnual Review of Neuroscience, 1997
- Peripheral Mechanisms of Pheromone Reception in MothsChemical Senses, 1996
- Functional Specialization of Olfactory Glomeruli in a MothScience, 1992
- Electroantennogram responses of five Lepidoptera species to 26 general odourantsJournal of Insect Physiology, 1990
- A new pheromone of the silkworm moth Bombyx moriThe Science of Nature, 1978