Expression of Activated MEK1 in Differentiating Epidermal Cells Is Sufficient to Generate Hyperproliferative and Inflammatory Skin Lesions
- 1 September 2004
- journal article
- Published by Elsevier in Journal of Investigative Dermatology
- Vol. 123 (3), 503-515
- https://doi.org/10.1111/j.0022-202x.2004.23225.x
Abstract
No abstract availableKeywords
Funding Information
- Cancer Research UK
This publication has 71 references indexed in Scilit:
- Manipulation of stem cell proliferation and lineage commitment:visualisation of label-retaining cells in wholemounts of mouse epidermisDevelopment, 2003
- Regulation of Interleukin-1α Expression by Integrins and Epidermal Growth Factor Receptor in Keratinocytes from a Mouse Model of Inflammatory Skin DiseaseJournal of Biological Chemistry, 2003
- Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiationOncogene, 2002
- A Dual Signaling Cascade That Regulates the Ectodomain Shedding of Heparin-binding Epidermal Growth Factor-like Growth FactorJournal of Biological Chemistry, 2001
- Analysis of cultured keratinocytes from a transgenic mouse model of psoriasis: effects of suprabasal integrin expression on keratinocyte adhesion, proliferation and terminal differentiationExperimental Dermatology, 1999
- Role of γδ T Lymphocytes in Immune Response in Humans and MiceCritical Reviews in Immunology, 1998
- Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell linesCurrent Biology, 1995
- Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v‐Ha‐ras oncogeneMolecular Carcinogenesis, 1993
- Modulation of interleukin‐1α mRNA expression in mouse epidermis by tumor promoters and antagonistsMolecular Carcinogenesis, 1993
- Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody.The Journal of Experimental Medicine, 1986