Postoperative radiotherapy in rectosigmoid cancer Dukes' B and C
- 1 October 1982
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 46 (4), 551-556
- https://doi.org/10.1038/bjc.1982.239
Abstract
The design, and complications seen during the first 2 years, of a randomized trial of postoperative radiotherapy for rectosigmoid cancer Dukes' B and C are presented and discussed. It is concluded that the present complication rate—below 10% in 221 patients—permits continuation of the intake, which is planned to include 550 patients, to demonstrate a possible increase in crude 5-year survival by 15% (60-75% in Dukes' B and 25-40% in Dukes' C), on the basis of a 0·01 significance level and a probability that the experiment will be successful of 0·90.Keywords
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