Transient embryonic antigens in the chick

Abstract

Immunochemical analysis of the 9-day chick brain with 9-day brain antiserum reveals significant amounts of two different groups of antigens. One group consists of at least three antigens. The other group consists of at least two antigens. Comparison of 9-day brain with other 9-day organs and with adult organs, including adult brain, reveals that the group of three antigens are common antigens and that one of them is transient and disappears by hatching. It is further shown that of the group of two antigens at least one is neural-specific and transient and disappears from the brain by hatching.