For over three years the Insect Allergy Committee of the American Academy of Allergy has been compiling a registry of persons allergic to insect bites or stings. Registrants are persons who have volunteered to fill out an initial detailed questionnaire and respond to annual inquiry. They represent persons whose names and addresses were submitted in part by physicians (most of whom are not allergists) and from persons who wrote to the Academy of Allergy directly as a result of publicity in newspapers and lay magazines. A previous report has been made on 1,477 registrants.1By February 1964 over 3,000 completed questionnaires were returned to our files. Of these, 2,606 replies have been recorded on Keysort cards and analyzed. Many persons reported several reactions to separate stings. Of 2,606 registrants, 914 reported unusual reactions to more than one kind of insect. Reactions of different kinds could be elicited by different