Packed Red Cell Transfusions ‐ Improved Survival, Quality and Storage
- 1 December 1977
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 33 (6), 346-352
- https://doi.org/10.1111/j.1423-0410.1977.tb02255.x
Abstract
Various anticoagulant-preservative solutions were investigated with a view to determining which would give optimal shelf life of packed cells. Satisfactory 24-hour post-transfusion survival (>70%) after 28-day storage was obtained with citrate phosphate 277 mM dextrose, 0.25 mM adenine (CP2 x D-adenine). After addition of a rejuvenating electrolyte solution through a multiple closed plastic pack system, there was further improvement in viability, oxygen delivery capacity and metabolic activity of stored erythrocytes, with reduction in both plasma potassium and microaggregate numbers. No untoward reactions were observed during or after transfusion of 440 units of rejuvenated blood.This publication has 13 references indexed in Scilit:
- The Quality of Over‐ and Undercollected Blood for TransfusionTransfusion, 1976
- The quality of over- and undercollected blood for transfusionTransfusion, 1976
- A Clinical Evaluation of Citrate‐Phosphate‐Dextrose‐Adenine BloodVox Sanguinis, 1975
- A Rapid Method for Obtaining the Half Saturation Tension of Small Blood Samples Using a Standard Clark Electrode SystemBritish Journal of Haematology, 1975
- Potassium Load in CPD‐Preserved Whole Blood and Two Types of Packed Red Blood CellsTransfusion, 1975
- In Vitro Metabolism of Packed Erythrocytes Stored in CPD‐AdenineTransfusion, 1975
- Effect of Osmotic Shrinking and Swelling of Red Cells on Whole Blood Oxygen AffinityScandinavian Journal of Clinical and Laboratory Investigation, 1974
- Pulmonary Microembolism after Blood TransfusionsAnnals of Surgery, 1973
- Complete Restoration of Oxygen Transport Function and 2,3‐Diphosphoglycerate Concentration in Stored BloodTransfusion, 1971
- Effect of Plasma Removal on Blood Stored in ACD with AdenineTransfusion, 1971