Physical and biological changes in an artificial fat emulsion during storage
- 30 September 1964
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 16 (10), 641-646
- https://doi.org/10.1111/j.2042-7158.1964.tb07382.x
Abstract
A soybean oil emulsion for parenteral nutrition has been stored for about 2 years at 4, 20 and 40°. During storage, the pH fell and the FFA concentration increased. The Michaelis-Menten constant (Km) and the maximum velocity of the lipoprotein-lipase reaction (Vmax) also increased. Gross particles were formed in the fat emulsion, and its toxicity increased with time. All these changes were most pronounced during storage at 40°.Keywords
Funding Information
- Reservationsanslaget, Karolinska Institutet
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