Formal total synthesis of erythromycin A. Part III. Synthesis of Woodward's carbamate key intermediate from a 1,7-dioxaspiro[5.5]undecane derivative of erythronolide A

Abstract

The spirocompound 1 which was obtained by total synthesis (Part I) and by degradation from erythromycin (Part II) was converted into carbamate product 15, a key intermediate in the Woodward's total synthesis of erythromycin A.