Studies in Cystic Fibrosis of the Pancreas

Abstract

THE measurement of the sodium and chloride concentration in body sweat is now a well established diagnostic procedure in the study of patients suspected of having cystic fibrosis of the pancreas. The original and important observation of the elevated sweat electrolytes in patients with cystic fibrosis by Darling et al.¹ imposed conditions for the collection of sweat that limited the application of their findings to the few institutions where the temperature and humidity of a specially constructed room could be carefully controlled (temperature of 90°F., and humidity of 50 per cent). Shwachman, Dooley and Higgins (1954) devised a practical method . . .